Goodgene¡¯s Cancer Mini Chip is a multiplex oligo DNA chip, which detects mutation or aberrant promoter methylation of multiple cancer-related genes as oncogene and tumor suppressor genes and thus provides highly accurate, quick and cost effective diagnosis of cancer.? Each Goodgene¡¯s Cancer Mini Chip comprises two types of oligo-chips. One is sequenced by hybridization (SBH) oligo-chip, on which hybridization reaction is carried out between multiple oligonucleotide probes of the chip and PCR products of sample DNA using the conventional 2-color scanner.? The other chip is a mini sequencing oligo-chip, on which a special form of sequencing reaction is carried out, using 2- or 4-color fluorescence dyes (fluorescence labelled dideoxy terminators). The mini sequencing oligo-chip can detect a point mutation or a change of deletion, insertion or aberrant promoter methylation and SNP accurately and quickly. This can save a lot of money and time as compare with conventional sequencing analysis.